Study on the Accuracy of Determining the Responsible Vessel in Medium Vessel Occlusive Stroke Based on Multi-type CT Evaluation
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Xuanwu Hospital, Beijing
- Enrollment
- 622
- Locations
- 1
- Primary Endpoint
- The difference in accuracy between the evaluation of MeVO stroke using multimode CT and that using NCCT+CTA
Study Overview
Brief Summary
To evaluate the accuracy of diagnosing the qualifying artery in patients with medium vessel occlusion stroke based on multimodal CT
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients with acute ischemic stroke, without restrictions on gender
- •Age ≥ 18 years old
- •The time from onset to treatment is within 24 hours (the onset time is defined as the "last-well-time", and the treatment plan is determined according to the patient's wishes and local clinical experience)
- •Before the treatment, CT, CTA and CTP examinations were conducted, and the relevant clinical data were complete.
Exclusion Criteria
- •Patients with acute intracranial hemorrhage
- •Patients whose CTP original images cannot be processed by the CTP post-processing software
- •Patients for whom the DICOM format image data of CT, CTP original images and MRI images cannot be obtained, or whose image quality is poor due to various reasons
Arms & Interventions
NCCT+CTA group
The attending physicians of neurology (with more than 5 years of experience in neuroimaging interpretation and not relevant to this study), without knowing the final radiological report, DSA, MRI results and clinical manifestations, only used baseline non-contrast CT (NCCT) and CTA to determine whether the included cases had moderate vascular occlusion. And record the qualifying artery
NCCT+CTA+CTP group
The attending physicians of neurology (with more than 5 years of experience in neuroimaging interpretation and not relevant to this study), without knowing the final radiological report, DSA, MRI results and clinical manifestations, only used baseline non-contrast CT (NCCT) , CTA and CTP to determine whether the included cases had moderate vascular occlusion. And record the qualifying artery
Outcomes
Primary Outcomes
The difference in accuracy between the evaluation of MeVO stroke using multimode CT and that using NCCT+CTA
Time Frame: at baseline
The difference in accuracy between the evaluation of MeVO stroke using multimode CT and that using NCCT+CTA
Secondary Outcomes
- The time required by the reader to identify the qualifying artery before and after using CTP(at baseline)
- The consistency between the core infarction volume evaluated based on CTP and the final infarction volume obtained from MRI examination within 7 days after the onset(7 days after the onset)