Are physiotherapy treatments feasible for patients with low oxygen levels after surgery?

Not Applicable

Completed

• Conditions: Abdominal surgery; Hypoxaemia; Surgery - Other surgery; Postoperative pulmonary complication; Physical Medicine / Rehabilitation - Physiotherapy; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12622000839707
• Lead Sponsor: Metro South Health

Brief Summary

Results are not yet available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-06-15
• Study Completion: 2023-10-13
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Major elective or non-elective abdominal surgery (open abdominal incision >5cm, or when anesthetic time >3 hours: laparoscopy or robotic surgery to the abdomen), extubated within 24hrs of surgery, age greater than or equal to 18 years, hypoxaemia while self-ventilating via a natural airway at least 3 hours after extubation and within 72 hours following abdominal surgery. Hypoxaemia is defined by a positive Air Test 90 (oxyhaemoglobin saturations <90% within 2 minutes of breathing room air) or if the Air Test 90 is not able to be conducted, a ratio of partial pressure of oxygen to fraction of inspired oxygen <300, where an arterial blood gas is available.

Exclusion Criteria

Unable to collaborate due to language or severe cognitive impairment, pregnancy, oesophagectomy, tracheostomy, previously participated in PHYSIO+++, current enrolment in a trial with similar therapies or outcomes, patients managed under airborne or droplet precautions, preoperative muscle weakness necessitating assistance to cough (for example a neuromuscular disorder or spinal cord injury), refusal to participate, not able to be recruited within 8 hours of screening as eligible, and those who do not receive medical clearance to participate in the trial due to (a) imminent (anticipated within 12hours of study inclusion) surgery, palliation, reintubation or the need for continuous medically prescribed NIV/CPAP (b) profound respiratory failure or cardiovascular instability (c) NIV contraindicated.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Accrual - the rate of patient recruitment (number of patients recruited to the trial per week) as determined by an audit of study screening and enrolment logs.[ The duration of the trial];Adherence to protocol - the total physiotherapist-led NIV time delivered (minutes) from enrolment until a trial end-point is met as determined by an audit of ward physio case report form[ Within the first 7 postoperative days<br>];Safety - The incidence of adverse events during or within 15mins following physiotherapy interventions as determined by clinical assessment recorded in the ward physiotherapist case report form and data in medical records.<br>Examples of adverse events are physiological changes (blood pressure, heart rate or rhythm changes, oxygenation) or significant patient reported events (pain/claustrophobia/vomiting).[ Within the first seven postoperative days]