Translation and Validation of the Intensive Care Unit Mobility Scale (IMS)

Completed

• Conditions: Muscle Weakness; Critical Illness; Early Mobilization; Mechanical Ventilation Complication

• Registration Number: NCT05591950
• Lead Sponsor: Charite University, Berlin, Germany

Brief Summary

Intensive care unit acquired weakness (ICUAW) is a common issue in critically ill patients. Early mobilization can reduce the occurrence of ICUAW. This requires a standardized procedure based on validated scales. One such scale is Carol Hodgson's ICU Mobility Scale (IMS).

The subject of the study is the translation of the IMS into German and the validation of its reliability and predictive power with regard to various clinical outcomes. Furthermore we want to investigate the communication about the mobilisation status of ICU-patients between the different medical disciplines that are involved in patient care.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-08-17
• Study First Submitted QC: 2022-10-20
• Study First Posted: 2022-10-24
• Study Start: 2023-01-24
• Primary Completion: 2024-11-11
• Study Completion: 2025-02-20
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-21
• Last Update Posted: 2025-04-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Critically ill adults (age: ≥ 18 years)
• Expected length of stay in ICU > 24h
• Ventilation support

Exclusion Criteria

• Patients transferred from other ICUs
• Patients with pre-existing functional limitations
• Patients with functional limitations due to the admission diagnosis (e.g. stroke. with hemiparesis)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Predictive validity of the IMS	approximate 28 days (till ICU discharge)	Predictive validity of the IMS-score performed in the first 24 hours after admission to the ICU for the length of stay in the ICU

Secondary Outcome Measures

Name	Time	Method
Discharge location	approximate at 28 days (at hospital discharge)	If the patient was discharged home or to another facility at hospital discharge
Duration of mechanical ventilation	approximate 28 days (till ICU discharge)	Duration of invasive mechanical ventilator dependency
MRC Score	approximate 28 days (till ICU discharge)	Muscle strength at ICU discharge measured using the Medical Research Council score
ICU mortality	approximate 28 days (till ICU discharge)	Mortality during ICU stay
Muscle strength	approximate 28 days (till ICU discharge)	Muscle strength at ICU discharge measured using hand grip strength
IMS during the ICU stay	approximate 28 days (till ICU discharge)	achieved mobilization level during the ICU stay using the ICU Mobility Scale (IMS)
in-hospital mortality	approximate 28 days (till discharge)	Mortality during the Hospital stay
90-day mortality	at 90 days	Mortality at 90 days
90-day function	at 90 days	Physical function of the patient at 90 days
ICU-LOS	approximate 28 days (till ICU discharge)	Length of stay in the ICU
Hospital LOS	approximate 28 days (till discharge)	Length of stay in the hospital

Trial Locations

Locations (1)

Charité - Univiversitätsmedizin Berlin; 🇩🇪 Berlin, Germany