The Development of Diagnostic Biomarker Panels for Hepatitis and Liver Cancer

• Conditions: Carcinoma,Hepatocellular; Hepatitis B,Chronic

• Registration Number: NCT01310062
• Lead Sponsor: Ministry of Health, Malaysia

Brief Summary

More recent studies have shown that the HBV-infected population has a greater risk of development of hepatocellular carcinoma. Nevertheless, there are still a significant number of people chronically infected by HBV who do not develop the complication. Hence, there exist biological markers that could be indicator for the disease-inducing and carcinogenic potential of the virus.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-08
• Status Verified: 2011-03
• Study First Submitted: 2011-03-04
• Study First Submitted QC: 2011-03-04
• Last Update Submitted: 2011-03-04
• Study First Posted: 2011-03-07
• Last Update Posted: 2011-03-07
• Study Completion: 2012-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1600

Inclusion Criteria

• Patients of at least 21 years old on day of giving consent for study
• Patients must be able and wiling to give an informed consent
• Patient with chronic HBV infection
• Patient with active hepatocellular carcinoma and chronic hepatitis B
• Healthy subjects

Exclusion Criteria

• Patients who have co-infection with HIV or chronic hepatitis C
• Subjects with other types of cancer

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (8)

Lam Wah Ee Hospital; 🇲🇾 Pulau Pinang, Malaysia

Penang Hospital; 🇲🇾 Pulau Pinang, Malaysia

Selayang Hospital; 🇲🇾 Selayang, Selangor, Malaysia

Kuala Lumpur Hospital; 🇲🇾 Kuala Lumpur, Wilayah Persekutuan, Malaysia

Island Hospital; 🇲🇾 Pulau Pinang, Malaysia

Sultanah Bahiyah Hospital; 🇲🇾 Alor Star, Kedah, Malaysia

Queen Elizabeth Hospital; 🇲🇾 Kota Kinabalu, Sabah, Malaysia

Hospital Umum Kuching Sarawak; 🇲🇾 Kuching, Sarawak, Malaysia