跳至主要内容
临床试验/CTRI/2025/02/080681
CTRI/2025/02/080681招募中Unknown

Study to Compare Effects Of Isobaric Injection Levobupivacaine and Isobaric Injection Ropivacaine In Labor Analgesia

Government Medical College Jalaun Orai1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2025年2月20日最近更新:

试验速览

阶段
Unknown
状态
招募中
发起方
入组人数
90
试验地点
1
主要终点
Maternal blood pressure

研究概览

简要总结

This  study was taken to  compare the effects on the labor and neonates of segmental epidural analgesia conducted  with Levobupivacaine and  Ropivacaine with fentanyl as opioid as adjuvant . 90 parturients were included in the study. They were randomly divided in two groups. patients received levobupivacaine and ropivacaine ,  Epinephrine was not added to local anesthetics. The first dose was 25 mg of levobupivacaine  0.25% (10 ml) and 10 micro gram of inj. Fentanyl and 37.5 mg for Ropivacaine 0.375% (10 ml). Reinjections occurred every 60 min for levobupivacaine ( 10 mg)  and ever 60 min for Ropivacaine (15  mg).. Umbilical cord blood was drawn for pH determination.

Patients in both the groups were compared for Maternal  blood pressure, pain relief, preservation of lower limb motor power, duration and progress of labour, and foetal outcome were evaluated , and need for emergency caesarean section is considered

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant, Investigator and Outcome Assessor Blinded

入排标准

年龄范围
18.00 Year(s) 至 40.00 Year(s)(—)
性别
Female

入选标准

  • all pregnant females of age 18 years TO 40 years.

排除标准

  • 1 Uncontrolled diabetes and hypertension.
  • 2 Chronic renal diseases 3 Chronic Anemia 4 I.H.D. or any other cardiac condition.
  • 5 Peripheral vascular disease.

结局指标

主要结局

Maternal blood pressure

时间窗: BASELINE, 6 HOURS AND 12 HOURS

pain relief

时间窗: BASELINE, 6 HOURS AND 12 HOURS

preservation of lower limb motor power

时间窗: BASELINE, 6 HOURS AND 12 HOURS

duration and progress of labor

时间窗: BASELINE, 6 HOURS AND 12 HOURS

fetal outcome were evaluated

时间窗: BASELINE, 6 HOURS AND 12 HOURS

次要结局

  • hemodynamic stability(12 HOURS AND 24 HOURS AFTER SURGERY)

研究者

发起方
Government Medical College Jalaun Orai
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Anil Kumar

Government Medical College Jalaun

研究点 (1)

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