Study to Compare Effects Of Isobaric Injection Levobupivacaine and Isobaric Injection Ropivacaine In Labor Analgesia
试验速览
- 阶段
- Unknown
- 状态
- 招募中
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Maternal blood pressure
研究概览
简要总结
This study was taken to compare the effects on the labor and neonates of segmental epidural analgesia conducted with Levobupivacaine and Ropivacaine with fentanyl as opioid as adjuvant . 90 parturients were included in the study. They were randomly divided in two groups. patients received levobupivacaine and ropivacaine , Epinephrine was not added to local anesthetics. The first dose was 25 mg of levobupivacaine 0.25% (10 ml) and 10 micro gram of inj. Fentanyl and 37.5 mg for Ropivacaine 0.375% (10 ml). Reinjections occurred every 60 min for levobupivacaine ( 10 mg) and ever 60 min for Ropivacaine (15 mg).. Umbilical cord blood was drawn for pH determination.
Patients in both the groups were compared for Maternal blood pressure, pain relief, preservation of lower limb motor power, duration and progress of labour, and foetal outcome were evaluated , and need for emergency caesarean section is considered
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)(—)
- 性别
- Female
入选标准
- •all pregnant females of age 18 years TO 40 years.
排除标准
- •1 Uncontrolled diabetes and hypertension.
- •2 Chronic renal diseases 3 Chronic Anemia 4 I.H.D. or any other cardiac condition.
- •5 Peripheral vascular disease.
结局指标
主要结局
Maternal blood pressure
时间窗: BASELINE, 6 HOURS AND 12 HOURS
pain relief
时间窗: BASELINE, 6 HOURS AND 12 HOURS
preservation of lower limb motor power
时间窗: BASELINE, 6 HOURS AND 12 HOURS
duration and progress of labor
时间窗: BASELINE, 6 HOURS AND 12 HOURS
fetal outcome were evaluated
时间窗: BASELINE, 6 HOURS AND 12 HOURS
次要结局
- hemodynamic stability(12 HOURS AND 24 HOURS AFTER SURGERY)
研究者
Dr Anil Kumar
Government Medical College Jalaun
