Prospective, controlled intervention study to optimize bowel evacuation and stimulation in extremely premature infants

Not Applicable

Recruiting

• Conditions: P07.01; P07.02

• Registration Number: DRKS00024191
• Lead Sponsor: Klinik für Neonatologie und allgemeine Pädiatrie Klinikum Kassel

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-02-04
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

• Premature babies up to the 2nd LT = 28th week of pregnancy or <1000g upon admission
•> 24h inpatient stay
• No spontaneous meconium loss after 24 hours

Exclusion Criteria

• Missing declaration of consent from the legal guardian
• Palliative care patients whose therapy has been discontinued
• Premature babies with underlying syndromes (e.g. trisomy 13, 18 or 21)
• Premature babies with proven passage disorders or atresia

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of intestinal complications:<br>Intestinal perforation, necrotizing enterocolitis, meconium plug syndrome

Secondary Outcome Measures

Name	Time	Method
• Duration of parenteral nutrition (h)<br>• Number and amount of gastric remains [frequency and ml / day]<br>• Weight development (increase / decrease in g / week)