Effect of Diode Laser on Post-operative Pain After Endodontic Treatment in Teeth With Apical Periodontitis

Not Applicable

Completed

• Conditions: Apical Periodontitis; Postoperative Pain
• Interventions: Device: Medency Primo Diode Laser Device (Medency, Vicenza, Italy); Procedure: 2.5% NaOCl, %17 EDTA, Distilled water, 30-gauge, side-opening needle (Canal Clean, Biodent, South Korea),

• Registration Number: NCT04486196
• Lead Sponsor: Biruni University

Brief Summary

Aim: This study aims to assess the effect of root canal disinfection with a 980 µm diode laser following chemomechanical root canal preparation on the severity of pain after root canal treatment (RCT).

Materials and Methods: In present study, asymptomatic, single-rooted teeth with periapical index (PAI) score 3 or 4 were included. All patients were treated with two visits of root canal treatment including dressing with calcium hydroxide. Patients were randomly divided into two groups (n: 28). 'Control (no laser)': The final irrigation was performed using 5ml 2.5% NaOCI, followed by 5 ml 17% EDTA and 5 ml distilled water. 'Laser Disinfection (LD)': Root canals were irradiated with 980 µm diode laser after final irrigation at both visits. The pain levels were evaluated using visual analog scale (VAS) after 8, 24, 48 hours and 7 days. In addition, analgesic intake and time intervals were recorded by patients. The collected data were statistically analyzed with the Chi-square and Mann-Whitney U test (p\<0.05).

Detailed Description

Not available

Study Timeline

• Study Start: 2019-04-08
• Primary Completion: 2019-11-02
• Study Completion: 2019-11-20
• Status Verified: 2020-07
• Study First Submitted: 2020-07-15
• Study First Submitted QC: 2020-07-22
• Last Update Submitted: 2020-07-22
• Study First Posted: 2020-07-24
• Last Update Posted: 2020-07-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Healthy patients
• Patients that had asymptomatic, single-rooted teeth with PAI score 3 or 4

Exclusion Criteria

• antibiotic use with in the last month,
• anti-inflammatory analgesic use within the last five days,
• systemic disorder, pregnancy or lactation,
• traumatic occlusion,
• presence of other teeth requiring RCT,
• teeth with root canal fillings,
• calcified canals,
• root resorption,
• periodontal diseases,
• sinus tracts
• severe crown destruction preventing rubber-dam application

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Laser Disinfection (LD) Group	Medency Primo Diode Laser Device (Medency, Vicenza, Italy)	After final irrigation was performed using 5ml 2.5% NaOCI, followed by 5 ml 17% EDTA for 3 min and 5 ml distilled water, root canals were irradiated with 980 nm diode laser coupled with optical fiber 200 µm with setting at the average power 1.2-W in pulsed mode. 10 seconds irradiation followed by 10 seconds pause, which comprised one lasting cycle. This cycle was applied 4 times for each root canal. The optical fiber (Medency) was inserted 1 mm short of the apex and the root canals were slowly (at a speed of 2mm/s) irradiated from apical to coronal in continuous circling movements to treat all dentinal tubules in one cycle for each power.
Control (No Laser) Group	2.5% NaOCl, %17 EDTA, Distilled water, 30-gauge, side-opening needle (Canal Clean, Biodent, South Korea),	The final irrigation was performed using 5ml 2.5% NaOCI, followed by 5 ml 17% EDTA for 3 min and 5 ml distilled water.

Primary Outcome Measures

Name	Time	Method
Post-operative pain	7 days	Post-operative pain levels in each group will be assessed by visual analog scale (VAS).The pain levels will be evaluated after 8, 24, 48 hours and 7 days.

Secondary Outcome Measures

Name	Time	Method
Analgesic intake	7 days	After first and second appointments, analgesic use and time intervals will be recorded.

Trial Locations

Locations (1)

Biruni University; 🇹🇷 İstanbul, Turkey