The effect of ginger consumption in patients with multiple sclerosis
- Conditions
- Multiple sclerosis.Multiple sclerosis
- Registration Number
- IRCT20180818040827N3
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Having relapsing-remitting multiple sclerosis according to the 2017 revisions of the McDonald diagnostic criteria
Age between 18-50 years
Non-menopausal women
Disability status score of less than or equal to 4.5 based on Expanded Disability Status Scale
No multiple sclerosis attack or corticosteroid therapy for at least 30 days
No change in multiple sclerosis medications for at least 6 months
Ability and willingness to participate in the study
Having other serious diseases such as other autoimmune disorders or cancers
Pregnancy
Multiple sclerosis attack or corticosteroid therapy during the intervention
Change in multiple sclerosis medications during the intervention
Allergic reactions to ginger or placebo supplements
Consumption of less than 90% of ginger or placebo supplements
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Score of disability status. Timepoint: Before and after the intervention. Method of measurement: Expanded Disability Status Scale.;Serum levels of interleukin-17. Timepoint: Before and after the intervention. Method of measurement: Assay kit.;Serum levels of nitric oxide metabolites. Timepoint: Before and after the intervention. Method of measurement: Assay kit.
- Secondary Outcome Measures
Name Time Method Serum levels of neurofilament light polypeptide. Timepoint: Before and after the intervention. Method of measurement: Assay kit.;Serum levels of matrix metalloproteinase-9. Timepoint: Before and after the intervention. Method of measurement: Assay kit.;Differential leukocyte count. Timepoint: Before and after the intervention. Method of measurement: Cell counter machine.;Score of quality of life. Timepoint: Before and after the intervention. Method of measurement: Multiple Sclerosis Impact Scale.;Score of gastrointestinal symptoms. Timepoint: Before and after the intervention. Method of measurement: Visual Analogue Scale.;Hematological indices. Timepoint: Before and after the intervention. Method of measurement: Cell counter machine.;Body mass index. Timepoint: Before and after the intervention. Method of measurement: Weighing scale and measuring tape.