Perioperative Risk Calculator

Active, not recruiting

• Conditions: Perioperative/Postoperative Complications

• Registration Number: NCT04092933
• Lead Sponsor: Technical University of Munich

Brief Summary

The aim of this project is to develop a machine-learning model for calculating the risk of postoperative complications. In addition to the data collected during the premedication, the model will include all intraoperative values recorded in the Patient Data Management System (PDMS), which include not only vital and respiratory parameters, but also medication and doses, intraoperative events and times. Postoperative complications are defined according to their severity according to the Clavien-Dindo score (Dindo, Demartines et al., 2004) and are collected from the data available in the health information system (HIS).

The machine-learning model is created using an extreme-gradient boosting algorithm which has been updated with new data from the year 2021 to ensure accuracy of the model.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-05-01
• Study First Submitted: 2019-07-08
• Study First Submitted QC: 2019-09-16
• Study First Posted: 2019-09-17
• Primary Completion: 2022-09-30
• Status Verified: 2023-10
• Last Update Submitted: 2023-11-21
• Last Update Posted: 2023-11-22
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 175559

Inclusion Criteria

• all patients who underwent surgery with anesthesia

Exclusion Criteria

• none

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
postoperative complications	30 days	Postoperative complications are classified by means of the Clavien-Dindo-Score.; The Clavien-Dindo-Score describes classes of severity of postoperative complications: Grade I: any deviation from the normal postoperative course without the need for pharmacological treatment or surgical, endoscopic and radiological interventions Grade II: requiring pharmacological treatment Grade IIIa: requiring surgical, endoscopic or radiological intervention not under general anesthesia Grade IIIb: requiring surgical, endoscopic or radiological intervention under general anesthesia Grade IVa: single organ dysfunction Grade IVb: multiorgandysfunction Grade V: death of a patient

Secondary Outcome Measures

Name	Time	Method
in-hospital mortality	30 days	mortality within hospital stay