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Is the clinical and cost-effectiveness of open surgery for severe occlusive disease of the aorta and iliac arteries superior to newer endovascular (keyhole) treatment? The EVOCC Trial

Not Applicable
Conditions
Severe occlusive aorto-iliac disease
Circulatory System
Registration Number
ISRCTN14591444
Lead Sponsor
niversity of Leicester
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Ongoing
Sex
All
Target Recruitment
628
Inclusion Criteria

Main Trial
1. Age > = 18 years (no upper age limit)
2. Presence of symptomatic PAD (tissue loss and/or rest pain and/or lifestyle limiting claudication)
3. Severe aorto-iliac occlusive PAD defined as Inter-Society Consensus for the Management of Peripheral Arterial Disease” (TASC II) class C or class D
4. Patient discussed in a local vascular Multi-Disciplinary Team (MDT) meeting and deemed suitable for open surgery or endovascular treatment.
5. Patient willing and able to give consent and commit to study follow-up.
6. An ability to understand written English or availability of a translator to explain the trial documentation

Communication Study (Patients)
1. Patient willing and able to give consent
2. An ability to understand written English or availability of a translator to explain the study documentation
3. Involved with research visits with nurses and/or doctors that have provided consent for the HCP Communication Study (where related to audio-recording of research visits)

Communication Study (Healthcare Providers)
1. Willing and able to give consent
2. Involved with research visits with patients that have provided consent for the Communication Study (where related to audio-recording of research visits)

Exclusion Criteria

Allergy to iodinated intravascular contrast agent including: Iopromide, Iodamide, Iohexol, ioversol, Ioxilan, Iopamidole.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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