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Clinical Trials/NCT05589519
NCT05589519
Terminated
N/A

Rehabilitation of Partial Edentulism Through the Use of Polyetheretherketone (PEEK) Prosthetic 3' Unit Fixed Prosthesis Supported by Dental Implants.

Malo Clinic1 site in 1 country5 target enrollmentOctober 3, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Prosthesis Survival
Sponsor
Malo Clinic
Enrollment
5
Locations
1
Primary Endpoint
Survival of the prosthesis
Status
Terminated
Last Updated
8 months ago

Overview

Brief Summary

The goal of this observational study is to evaluate the outcome of a Poly-ether-ether-ketone - used in partial implant-supported rehabilitations after one year of follow-up. The main question it aims to answer is:

- What is the survival outcome of partial implant-supported prosthesis using Poly-ether-ether-ketone? The participants already rehabilitated with dental implants will receive a definitive 3 unit prosthesis incorporating Poly-ether-ehter-ketone.

Detailed Description

Following the previous study on the full-arch rehabilitation of edentulous jaws using hybrid prostheses with polyetheretherketone (PEEK) infrastructure and acrylic resin teeth supported by implants in immediate function inserted through the All-on-4 concept it is necessary to further extend the evaluation to the partial rehabilitation using 3 Unit fixed prostheses supported by dental implants. To test this, the study design to be used will be a single-centre, prospective, observational cohort study to evaluate the short term outcome of fixed prosthetic implant-supported rehabilitations. The sample of this study consists in 10 patients consecutively treated. The cohort will be evaluated at 4 to 8 weeks, 6 months and 12 months after dental loading and annually thereafter as long as the patient is willing, regarding: prosthetic survival including repair and relining, implant survival, marginal bone resorption, incidence of mechanical complications \[loosening or fracture of prosthetic components), biological complications (peri-implant infection, suppuration, abscess, fistulae), patient tissue reaction, aesthetic examination including denture staining, colour stability and anatomic form; patients' in-mouth comfort and quality of life using the Oral Health Impact Profile OHIP-14 questionnaire; and assessment of prosthetic preparation (technician satisfaction), laboratory preparation time, clinical operative time and costs.

Registry
clinicaltrials.gov
Start Date
October 3, 2022
End Date
March 31, 2025
Last Updated
8 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Malo Clinic
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients rehabilitated with dental implants and a 3 unit Bridge where the molars are missing in one jaw, with at least both canines present;
  • Subjects who, in the opinion of the Investigator, are able to understand this clinical study, co-operate with the procedures and are willing to return to the clinic for all the required post-operative follow-ups;
  • Subjects who are able to give voluntary, written informed consent to participate in this clinical study and from whom consent has been obtained.

Exclusion Criteria

  • Female Subjects who are pregnant;
  • Subjects who are known drug or alcohol abusers or with psychological disorders that could affect follow-ups or treatment outcomes;
  • Subjects who are currently enrolled in a clinical study;
  • Subjects requiring or currently having ongoing orthodontic treatment.

Outcomes

Primary Outcomes

Survival of the prosthesis

Time Frame: one year

Evaluation of the survival for the implant-supported prosthesis; nominal (survival,failure)

Secondary Outcomes

  • Patient tissue reaction(one year)
  • ln mouth comfort(one year)
  • Oral Health Impact Profile OHIP-14(one year)
  • Laboratory preparation time(one year)
  • Clinical operative time(one year)
  • Survival of the implants(one year)
  • Incidence of biological complications(one year)
  • Incidence of mechanical complications(one year)
  • Marginal bone resorption(one year)
  • Denture staining(one year)
  • Denture colour stability(one year)
  • Denture anatomic form(one year)

Study Sites (1)

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