Risk factor assessment for future arterial cardiovascular events in patients with unprovoked pulmonary embolism.
- Conditions
- Pulmonary embolismArterial cardiovascular eventsRisk factors
- Registration Number
- NL-OMON23577
- Lead Sponsor
- eiden University Medical Center
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 250
Consecutive patients presenting with an episode of unprovoked acute PE are potentially eligible for study inclusion. Acute PE is confirmed by at least one filling defect in the pulmonary arteries on CT scan or a high probability ventilation-perfusion (V/Q) lung scan. Unprovoked PE is defined as PE in absence of temporary risk factors (malignancy now or in previous 5 years, immobility > 3 days, recent long flight (< 7
days), recent surgery (< 4 weeks), plaster cast of extremity, pregnancy/post partum period, hormone replacement therapy or oral contraceptive use at time of diagnosis or patients with known thrombophilia (Factor V Leiden, Protein C or S deficiency)). Patients > 18 years having given written informed consent are eligible for study inclusion. Patients may present as follows:
1. Acute onset of PE for more than 14 days;
2. Provoked PE (see criteria mentioned above);
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method