Impact of cardiovascular risk factors on arterial wall thickness

Recruiting

• Conditions: hypertensie; atherosclerosis

• Registration Number: NL-OMON37428
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

Subjects with hypertension (diastolic >90 and/or systolic >140 and/or use of medication against hypertension) and their age- and sex-matched controls.;Subjects with hypertension have a blood pressure (after 5 min seated rest, measured twice) of >=140 systolic or >=90 diastolic blood pressure or the use of prescribed anti-hypertension medication.

Exclusion Criteria

For all subjects
- Diagnosis of cardiovascular disease
- Diabetes Mellitus type I or II
- smoking
- women on hormone replacement therapy
- Family history of acute cardiac death (< 50 years of brother/sister or father/mother).
- Hypercholesterolemia (>=6.5 mmol/L or use of statins).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1) Wall thickness<br /><br>2) Flow-mediated dilation</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>