The Incidence and Risk Factors for Cardiovascular Complication after Spine Surgery

Completed

• Registration Number: TCTR20211011003
• Lead Sponsor: eurological Institute of Thailand

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-06-30
• Study Start: 2021-10-11
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 1002

Inclusion Criteria

After approval by the Research Ethics Committee of the Neurological Institute of Thailand, a retrospective cohort study was done. The data was collected from patients who underwent spine surgery in single hospital, Neurological Institute of Thailand. The sample size was calculated from the estimating an infinite population proportion with n4studies software (Ngamjaras C. et al., The Thailand Research Fund, Prince of Songkla University, Songkla, Thailand, 2016). The incidence of cardiovascular complications after anesthesia in elderly patients undergoing orthopedic surgery was 2.3% based on the research of Chalacheewa and colleagues with the configuration of error (d) was 0.019. After substituting the values in the calculation formula, a sufficient sample is 863 patients plus a drop out of 20%. The final sample was 1,035 patients.
Data were collected within two years, from January 2018 to December 2019, using all inpatient medical records and an electronic anesthesia recording system. Patient datas were demographics including American Society of Anesthesiologists (ASA) physical status classification, laboratory finding, surgical data, and anesthesia-related, e.g., intraoperative blood pressure, amount of blood loss.
Cardiovascular complications were defined following the definition of Major adverse cardiovascular events (MACEs) that occur during perioperative and within 30 days postoperative period including cardiac arrest, acute congestive heart failure (acute CHF), acute myocardial infarction (acute MI), and acute stroke.

Exclusion Criteria

Data not complete

Study & Design

• Study Type: Observational
• Study Design: Not specified