Influence of Chronic Vascular Diseases on Transcranial Doppler Profiles in Critically Ill Patients

Completed

• Conditions: Respiration, Artificial; Sedated

• Registration Number: NCT02898389
• Lead Sponsor: Centre Hospitalier Universitaire de Nīmes

Brief Summary

The primary objective of this study is to show that cardiovascular risk factors associated with the chronic elevation of arterial resistance may be associated with "false" profiles of intracranial hypertension during transcranial doppler ultrasound of the middle cerebral arteries in intensive care unit patients. A "false" profile of intracranial hypertension is defined by a high pulsatility index without any intracranial pathology.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-06-14
• Study First Submitted: 2016-09-08
• Study First Submitted QC: 2016-09-08
• Study First Posted: 2016-09-13
• Primary Completion: 2018-09-14
• Study Completion: 2018-09-14
• Status Verified: 2020-08
• Last Update Submitted: 2020-08-11
• Last Update Posted: 2020-08-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 91

Inclusion Criteria

Not provided

Exclusion Criteria

• acute neurological disorder (brain trauma, infectious or immune meningitis, meningoencephalitis, ischemic or hemorrhagic stroke <3 months)
• pregnant woman
• person under guardianship
• prisoners
• recent carotid surgery (<1 month)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pulsatility index on the middle cerebral arteries	Day 0
Diastolic velocity at the middle cerebral arteries	Day 0
Mean velocity at the middle cerebral arteries	Day 0

Trial Locations

Locations (1)

CHU de Nîmes - Hôpital Universitaire Carémeau; 🇫🇷 Nîmes Cedex 09, France