Observational Study of BRAF Inhibitor Combination Therapy for BRAF mutant Metastatic Colorectal Cancer including Biomarker Research: BEETS trial(JACCRO CC-18)
- Conditions
- Colorectal Cancer
- Registration Number
- JPRN-UMIN000045530
- Lead Sponsor
- JACCRO
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 200
Not provided
(1) Patients with interstitial pneumonia or pulmonary fibrosis (2) Patients with a history of acute myocardial infarction or acute coronary syndrome (unstable angina, coronary artery bypass surgery, coronary angioplasty, stenting, etc.) within 6 months prior to enrollment (3) Patients with a history or current evidence of clinically significant congestive heart failure or cardiac arrhythmia within 6 months prior to enrollment (4) Patients with a history of clinically significant thromboembolic or cerebrovascular events within 6 months prior to enrollment (5) Patients with a history of chronic inflammatory bowel disease or Crohn's disease requiring medical intervention (immunomodulatory or immunosuppressive drugs or surgery) within 12 months prior to enrollment (6) Patients with active multiple cancers (7) Patients with active infectious diseases that require systemic treatment (8) Patients with positive HBs antigen, HCV antibody, or HIV antibody (9) Patients judged by the principal investigator or sub-investigator to be inappropriate for the safe conduct of this study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method