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Clinical Trials/NCT00508092
NCT00508092
Completed
N/A

Combined Nerve Blockade and Local Infiltration Anesthesia in Appendectomy - A Blinded Randomized Study

Royal Berkshire NHS Foundation Trust1 site in 1 country75 target enrollmentJanuary 2007

Overview

Phase
N/A
Intervention
Not specified
Conditions
Pain, Postoperative
Sponsor
Royal Berkshire NHS Foundation Trust
Enrollment
75
Locations
1
Primary Endpoint
Post operative pain score
Status
Completed
Last Updated
18 years ago

Overview

Brief Summary

The purpose of this study is to assess whether the use of local anesthetic to numb the nerves that run deeper in the abdominal wall gives better post operative pain control than just infiltrating local anesthetic to the wound edges.

Detailed Description

Local anesthetic is often administered during an operation to reduce post operative wound pain. Whilst this is frequently done during an appendectomy there is currently no evidence to suggest whether there is any benefit to the patient to injecting the local anesthetic deeper to block the nerves supplying abdominal wall sensation, compared to using it just in the skin around the wound. Comparison: Post operative pain scores following appendectomy for patients given skin infiltration of local anesthetic (pre incision), compared to patients given both preincision wound infiltration and deeper field infiltration with local anesthetic(deep to external oblique).

Registry
clinicaltrials.gov
Start Date
January 2007
End Date
TBD
Last Updated
18 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Lanz incision appendectomy as starting procedure, including those where an alternative cause for symptoms is found at operation and those where incision is later extended/changed (these may be sub grouped at time of analysis)
  • Consent obtained

Exclusion Criteria

  • Laparoscopic appendectomy
  • Appendectomy at time of laparotomy/other incision

Outcomes

Primary Outcomes

Post operative pain score

Time Frame: 1 hour, 4 hours, 8 hours, 24 hours and on discharge

Secondary Outcomes

  • Post operative nausea and vomiting(1 hour, 4 hours, 8 hours, 24 hours and on discharge)

Study Sites (1)

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