NCT06560099尚未招募不适用
Standard Oxytocin Versus High Dose Oxytocin to Control Postpartum Hemorrhage in High Risk Pregnancy During Elective Cesarean Section
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 39
- 主要终点
- blood loss
研究概览
简要总结
Controlling hemorrhage during and after a cesarean section reduces significantly maternal mortality and morbidity and the present study is important for detection of the effectiveness of routinely increasing the oxytocin dose instead of using the standard dose only in preventing postpartum hemorrhage and additional use of uterotonics in the first 24 hours after cesarean section for high risk pregnancy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •- Medical disorders ie: Hypertensive diseases with pregnancy - Diabetes Mellitus - Collagen diseases - Coagulopathies - Cardiac diseases - Anemia
- •History of postpartum hemorrhage
- •Placental disorders ie: placenta previa
- •Infertility and ICSI
- •High Parity
- •History of Endometriosis
- •Fetal disorders (IUGR, IUFD, Preterm, Congenital anomalies, oligohydramnios or polyhydramnios, macrosomia)
- •Preterm labor on uterine relaxants
- •Twins pregnancy
- •Patients on antiplatelets and anticoagulants
- •Uneventful antenatal care
排除标准
- •- Oxytocin Allergy
- •Normal uncomplicated pregnancy
- •Emergency cesarean section
- •Exhausted uterus due to trial of normal labor
- •Couvelaire uterus
研究组 & 干预措施
Group A (standard oxytocin dose)
Active Comparator
干预措施: Oxytocin (Drug)
Group B (high dose oxytocin)
Active Comparator
干预措施: Oxytocin (Drug)
结局指标
主要结局
blood loss
时间窗: at the end of the operation
measure blood in suction, towels and pads
次要结局
- haemoglobin(6 hours postoperative)
研究者
RAMY AHMED
Assistant Professor of Anesthesia
Ain Shams University
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