Primary Evaluation of Anti hyperglycemic Effect of internal septum of Juglans regia in patients with diabetes mellitus type II: A Double blind Randomized Clinical Trial

Tehran University of Medical Sciences0 个研究点目标入组 60 人开始时间: 待定最近更新: 2022年3月8日

适应症

试验速览

暂无简介。

•Obtain consent from patients
•Age between 25 and 70 year old
•HbA1C=7% and less than 9% and FPG = 130-250 mg / dl
•Take metformin and/or other anti-diabetic agents (in maximum and constant dose for three months) or metformin alone (in maximum and constant dose for three months)
•Constant diet and physical activity during the study (according to a questionnaire translated and validated into Persian)
•The patient's anti-diabetic medication regimen remained constant during the study
•No allergies to walnuts

•History of walnut allergy
•Immune system defects
•Pregnancy and lactation
•Cardiovascular disease (coronary artery ischemia, EF <45%)
•Take medications that change blood glucose levels (corticosteroids, tacrolimus, anti-AIDS drugs, antipsychotic drugs)
•Uncontrolled thyroid disease
•Acute infection
•History of diabetic ketoacidosis
•eGFR<60 ml/min
•Acute hepatitis (increase in ALT and AST to more than 10 to 20 times normal)
•Proliferative retinopathy
•Severe weight loss (at least 10% over 6 months)
•Consumption of any other medicine and herbal products, including walnuts

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