Impact of preoperative Vitamin D3 administration on postoperative hypocalcaemia in patients undergoing total thyroidectomy

Phase 4

• Conditions: benign thyroid conditions; E04.0; Nontoxic diffuse goitre

• Registration Number: DRKS00005615
• Lead Sponsor: Sana Klinikum Offenbach

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2014-01-13
• Study Completion: 2017-03-20
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 246

Inclusion Criteria

Written Informed Consent
Benign Thyroid Condition
Total Thyroidectomy

Exclusion Criteria

Age < 18 and > 85 of Years, Noncompliance with relevant study procedures, visit schedule and follow up , non-eligibility for and/or no reasonable access to outpatient care, pregnancy, present musculoscelettal disease or co-medication known to affect calcium metabolism (Vitamine D, Hydrochlorothiazides, estrogenes, glycosides), malignancy of the thyroid gland, competing therapies or procedures and or simultaneous participation in other clinical trials and withdrawal of informed consent

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary endpoint is defined as the number of participants with a postoperative serumcalcium of < 2,1 mmol/l at any of the in hospital days following surgery

Secondary Outcome Measures

Name	Time	Method
Time (Number of days) to discharge; Health-economic endpoints (hypocalcaemia questionnaire, SF 36®)