Taichi for Overweight/Obese Adolescent and Young Women With Polycystic Ovary Syndrome (PCOS)

Not Applicable

• Conditions: Polycystic Ovary Syndrome
• Interventions: Behavioral: Taichi; Behavioral: Self-monitored exercise

• Registration Number: NCT02608554
• Lead Sponsor: Heilongjiang University of Chinese Medicine

Brief Summary

The present study is a randomized pilot study, overweight/obese adolescent and young PCOS subjects will be assigned into two groups: Taichi arm and control arm. Hormonal profile and metabolic profile will be determined.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2015-11-17
• Study First Submitted QC: 2015-11-17
• Study First Posted: 2015-11-18
• Study Start: 2016-10
• Status Verified: 2019-12
• Last Update Submitted: 2019-12-23
• Last Update Posted: 2019-12-26
• Primary Completion: 2019-12-31
• Study Completion: 2020-03-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 50

Inclusion Criteria

• Women aged between 19 and 35 years;
• Diagnosis of PCOS according to the modified Rotterdam criteria;
• 2 years after menarche;
• Body mass index (BMI) equal to or greater than 23 kg/m*m.

Exclusion Criteria

• Administration of other medications known to affect reproductive function or metabolism within the past three months, including oral contraceptives, Gonadotropin-releasing hormone (GnRH) agonists and antagonists, anti androgens, gonadotropins, anti-obesity drugs, Chinese herbal medicines, anti diabetic drugs such as metformin and thiazolidinediones, somatostatin, diazoxide, and calcium channel blockers.
• Patients with other endocrine disorder including 21-hydroxylase deficiency, hyperprolactinemia, uncorrected thyroid disease, suspected Cushing's syndrome.
• Patients with known severe organ dysfunction or mental illness.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Taichi	Taichi	The 24 forms of simplified TCC recommended as the popular health sport by the General Administration of Sport of China were applied.
Self-monitored exercise	Self-monitored exercise	Exercise was self-monitored and consisted of brisk walking, cycling, jogging, or any other aerobic exercise.

Primary Outcome Measures

Name	Time	Method
Body mass index (BMI)	3 months

Secondary Outcome Measures

Name	Time	Method
Testosterone (T)	3 months
Follicle stimulating hormone (FSH)	3 months
Fasting plasma glucose (Glu)	3 months
Fasting insulin (Ins)	3 months
HOMA-IR	3 months	HOMA-IR = fasting insulin concentrations (mIU/L) ×fasting plasma glucose concentrations (mmol/L)/22.5
Ferriman-Gallwey score	3 months
Luteinizing hormone (LH)	3 months
Waist/hip ratio	3 months

Trial Locations

Locations (1)

First Affiliated Hospital, Heilongjiang University of Chinese Medicine; 🇨🇳 Harbin, Heilongjiang, China