PARASTERNAL BLOCKADE

Phase 3

Completed

• Conditions: Parasternal Block; Cardiac Surgery; Serum Lactate
• Interventions: Procedure: parasternal block; Diagnostic Test: Lactate serum level

• Registration Number: NCT06608290
• Lead Sponsor: Instituto Mexicano del Seguro Social

Brief Summary

Parasternal blockade has been related to a reduction of the postoperative inflammatory response, by inhibition of the stress response, leading to a better prognosis. Increased lactate level is a useful parameter in identifying patients at risk of postoperative morbidity and mortality. The objective was to evaluate the association between parasternal blockade and serum lactate level in patients undergoing cardiac surgery, both trans- and post-anesthesia. 86 patients between 60-70 years of age participated. An association was found between the application of parasternal blockade in cardiac surgery and the presence of lower trans and postanesthetic serum lactate levels.

Detailed Description

An analytical cross-sectional study in adult patients who underwent elective cardiac surgery. A total sample of 86 patients was obtained, 43 in the case group and 43 in the control group. Adult patients older than 18 years, of either sex, with ASA II-III, patients who underwent cardiac surgery with median sternotomy and use of cardiopulmonary bypass were included.

Study Timeline

• Study Start: 2022-01-01
• Primary Completion: 2022-12-31
• Status Verified: 2023-09
• Study Completion: 2024-09-02
• Study First Submitted: 2024-09-19
• Study First Submitted QC: 2024-09-20
• Last Update Submitted: 2024-09-20
• Study First Posted: 2024-09-23
• Last Update Posted: 2024-09-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 86

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Blockade	parasternal block	In patients which parasternal block has been applied
Blockade	Lactate serum level	In patients which parasternal block has been applied
Control	Lactate serum level	In patients which parasternal block has not been applied

Primary Outcome Measures

Name	Time	Method
Lactate serum levels	24 Hours	Blood samples were taken to identify serum lactate levels greater than 2 mmol/l and those that remained below this limit.

Trial Locations

Locations (1)

Unidad de Investigación Biomédica 02, Unidad Médica de alta especialidad, Hospital de Especialidades Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara 44329, México; 🇲🇽 Guadalajara, Jalisco, Mexico