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Clinical Trials/NCT06608290
NCT06608290
Completed
Phase 3

ASSOCIATION BETWEEN THE APPLICATION OF PARASTERNAL BLOCKADE AND SERUM LACTATE LEVEL IN TRANS- AND POST-ANESTHETIC STAGES IN CARDIAC SURGERY

Instituto Mexicano del Seguro Social1 site in 1 country86 target enrollmentJanuary 1, 2022

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Parasternal Block
Sponsor
Instituto Mexicano del Seguro Social
Enrollment
86
Locations
1
Primary Endpoint
Lactate serum levels
Status
Completed
Last Updated
last year

Overview

Brief Summary

Parasternal blockade has been related to a reduction of the postoperative inflammatory response, by inhibition of the stress response, leading to a better prognosis. Increased lactate level is a useful parameter in identifying patients at risk of postoperative morbidity and mortality. The objective was to evaluate the association between parasternal blockade and serum lactate level in patients undergoing cardiac surgery, both trans- and post-anesthesia. 86 patients between 60-70 years of age participated. An association was found between the application of parasternal blockade in cardiac surgery and the presence of lower trans and postanesthetic serum lactate levels.

Detailed Description

An analytical cross-sectional study in adult patients who underwent elective cardiac surgery. A total sample of 86 patients was obtained, 43 in the case group and 43 in the control group. Adult patients older than 18 years, of either sex, with ASA II-III, patients who underwent cardiac surgery with median sternotomy and use of cardiopulmonary bypass were included.

Registry
clinicaltrials.gov
Start Date
January 1, 2022
End Date
September 2, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Clotilde Fuentes-Orozco

Investigador Principal

Instituto Mexicano del Seguro Social

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Lactate serum levels

Time Frame: 24 Hours

Blood samples were taken to identify serum lactate levels greater than 2 mmol/l and those that remained below this limit.

Study Sites (1)

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