Comparison of general and spinal anesthesia on the body's defense systems in diabetic patients
Phase 2
- Conditions
- Diabetes.Insulin-dependent diabetes mellitus
- Registration Number
- IRCT201402208384N3
- Lead Sponsor
- Vice Chancellor for Research, Mashhad University of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 63
Inclusion Criteria
Diabetic patient with diabetic foot who were candidate for lower limb amputation.
Exclusion criteria: Lack of consent to participate in the study; Antioxidant supplements such as vitamin C; Neuraxial uplink block is prohibited; End-stage renal disease.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum total antioxidant capacity. Timepoint: Before induction, 1 hour after surgery. Method of measurement: Antioxidant Assay Kit.;Level of Serum Lipid Peroxidation. Timepoint: Before induction, 1 hour after surgery. Method of measurement: TBARS (Thiobarbitoric Acid Reactive Substances Assay kit).
- Secondary Outcome Measures
Name Time Method