The effect of general and spinal anesthesia on the level of inflammatory factors in hysterectomy surgery

Phase 3

Recruiting

• Conditions: Inflammatory factors after hysterectomy.; Abnormal uterine and vaginal bleeding, unspecified; N93.9

• Registration Number: IRCT20190819044559N4
• Lead Sponsor: Kerman University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 42

Inclusion Criteria

Patients who will undergo hysterectomy with different diagnoses are included in the study.

Exclusion Criteria

Patients with a history of any type of inflammatory and autoimmune disease
History of endocrine diseases
Severe neurological disease
Corticosteroid use in the three months before surgery
Evidence of any infectious disease

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
IL -17 serum level. Timepoint: Before intervention, 48 hours after intervention. Method of measurement: Enzyme-linked immunosorbent assay (ELISA).;IL-2 serum level. Timepoint: Before intervention, 48 hours after intervention. Method of measurement: Enzyme-linked immunosorbent assay (ELISA).;IL -6 serum level. Timepoint: Before intervention, 48 hours after intervention. Method of measurement: Enzyme-linked immunosorbent assay (ELISA).;TNF -a serum level. Timepoint: Before intervention, 48 hours after intervention. Method of measurement: Enzyme-linked immunosorbent assay (ELISA).;IL-10 serum level. Timepoint: Before intervention, 48 hours after intervention. Method of measurement: Enzyme-linked immunosorbent assay (ELISA).