Vitamin C Supplementation Plus Hypoglycemic Agents Versus Hypoglycemic Agents Alone in Type 2 Diabetes Mellitus
- Registration Number
- NCT01319734
- Lead Sponsor
- Al-Neelain University
- Brief Summary
Null hypothesis:
No significant effect of vitamin C 500 mg Supplementation on the severity of micro-vascular complications of type 2 Diabetes Mellitus (DM).
Alternative hypothesis:
There is a significant effect of vitamin C 500mg supplementation on the severity of the micro-vascular complications of type 2DM.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- clinical diagnosis of type 2DM
- patients in good health
- receiving oral hypoglycemic drugs
Exclusion Criteria
- Insulin dependent diabetes
- receiving vitamin complex
- smoking
- renal disease
- liver disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Vitamin C supplementation plus oral hypoglycemic agents arm Vitamin C This group will receive vitamin C supplementation 500mg daily for one month and then assessment will done for the patients. Type 2DM patients receiving oral hypoglycemic agents alone glyburide this group is the control group who receive oral hypoglycemic agents alone
- Primary Outcome Measures
Name Time Method improving the renal function the renal function will be measure at day 1 and after one month vitamin c supplementation act as an antioxidants which reduce the oxidative stress and then can improve the renal function.
- Secondary Outcome Measures
Name Time Method Vitamin C can improve the visual fields the visual field will be assesed at day 1 and after one month the damage of the eye can be prevented by decreasing the oxidative stress in the eye, this can be accomplished by vitamin C.
Trial Locations
- Locations (1)
Jaber abo aliz
🇸🇩Khartoum, Sudan