Expression of molecules that detect the presence of fat in the small intestine.

Not Applicable

• Conditions: Obesity; Healthy human physiology; Oral and Gastrointestinal - Normal oral and gastrointestinal development and function; Diet and Nutrition - Obesity

• Registration Number: ACTRN12611000390987
• Lead Sponsor: niversity of Adelaide

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-04-14
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patients aged 18-75 years, scheduled to undergo surveillance endoscopy at the Royal Adelaide Hospital.

Exclusion Criteria

-diffuse mucosal disease involving the upper gastrointestinal tract, including Crohn's disease, coeliac disease, or ischaemic changes, evident either macroscopically or on histopathological examination of mucosal biopsies, when the latter is clinically indicated.
-gastrointestinal symptoms
-ongoing anticoagulation or bleeding disorder, or use of anticoagulant drugs (e.g. aspirin, clopidogrel)

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Expression of mRNA and protein of CD36, GPR119, GPR120 and GPR40 in small intestinal biopsies.[Once only.]

Secondary Outcome Measures

Name	Time	Method
Habitual dietary intake, as assessed by the use of a Food Frequency Questionnaire.[Once only.]