The effectiveness of the placement of gold markers for irradiation of rectal cancer.
Completed
- Conditions
- Rectal cancerRectumcarcinoomEndeldarmkanker
- Registration Number
- NL-OMON20605
- Lead Sponsor
- KI-AV
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
•Histologically proven diagnosis of primary rectal adenocarcinoma
•Resectable rectal cancer
Exclusion Criteria
•Coagulopathy (prothrombin time < 50% of control; partial thromboplastin time > 50 seconds) or anticoagulantia (marcoumar or sintrom) that cannot be stopped
•Prior pelvic irradiation or surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The feasibility of fiducial marker placement, defined as the technical success (the ability to successfully place the fiducials at the desired locations in the tumour area).<br>
- Secondary Outcome Measures
Name Time Method - Patient safety: grade 3-4 complications (NCI-CTCAE version 4.0) or symptoms lasting more than two days.<br /><br>- Visibility of fiducial markers on MRI and CT<br /><br>- Migration of fiducial markers