Comparison of two drugs in spinal anaesthesia for lower limb orthopaedic surgeries

Not Applicable

• Conditions: Health Condition 1: S828- Other fractures of lower leg

• Registration Number: CTRI/2020/12/030033
• Lead Sponsor: Department of AnaesthesiologyGoverment medical college bhavnagar

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

ASA grades: I, II and III.

Participant undergoing lower limb surgery under subarachnoid block.

A written informed consent obtained from participant.

Exclusion Criteria

Participants having contraindications to subarachnoid block like congenital spinal anomalies, altered coagulation profile, local site skin infection.

Participants having severe psychiatric disorders like depression, dementia or any other psychiatric illness and are not compatible for subarachnoid block.

- Participants having neurological diseases like brain tumour, CNS syphilis, meningitis.

Spinal cord and peripheral nerve diseases, poliomyelitis, multiple sclerosis.

Participants with allergy to local anaesthetic drug or study drug.

Pregnant lady and lactating mother.

Chronic headache. eg.migraine.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the onset, peak, duration and regression of sensory and motor blockage in both groups. <br/ ><br>To compare the onset, peak, duration and regression of motor blockage in both groups. <br/ ><br>To compare period of postoperative analgesia in both groups. <br/ ><br>Timepoint: To measure vitals, and semsory and motor block effects at specific time interval. Time 0, after immediately giving spinal anaesthesia, and then at the time point of 1,2,3,5,10,15,30,60,90,120 mins and for post operative analgesia and effect regression 4 hours post operatively.

Secondary Outcome Measures

Name	Time	Method
to compare heamodynemic status of pt, and any side effects.Timepoint: Time 0(immediately after block) and then at 1,2,3,5,10,15,30,60,90,120 mins.