Diagnosing invasive fungal infections on DNA extracted from serum or plasma of immunocompromised patients with a suspected invasive pulmonary fungal infectio

• Conditions: invasive aspergillosis; invasive fungal infections; 10024324; 10024970

• Registration Number: NL-OMON50191
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 300

Inclusion Criteria

*18 years or older
*Lung CT showes lesions that fullfill the EORTC/MSG radiological criterium of
possible invasive fungal infection.
*A bronchoalveolar lavage is planned or has been performed <48hrs earlier

Exclusion Criteria

* Unable or unwilling to provide informed consent

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>All patients will be classified as proven, probable or possible, undetermined<br /><br>or no invasive pulmonary fungal infection according to the EORTC/MSG criteria.<br /><br>From the patients with probable or proven invasive aspergillosis, the number<br /><br>and percentages of patients samples producing a result by two different PCRs.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable</p><br>