Endometriosis and Risk Factors in Pregnancy, Labor and Delivery
试验速览
- 阶段
- 不适用
- 入组人数
- 350
- 试验地点
- 1
- 主要终点
- Gestational diabetes
研究概览
简要总结
The purpose of this study is to assess if endometriosis can be considered a risk factor for adverse obstetric and delivery outcomes
详细描述
This is a retrospective, observational, case-control study. Pregnancy, delivery and neonatal outcomes will be analyzed in two groups of patients (case and control group): women with diagnosis of endometriosis histologically confirmed and women without endometriosis. Women with endometriosis will be matched to controls by age. A database with general medical and gynecological history, pregnancy course, delivery mode and newborn conditions will be analyzed.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Pregnant women who delivered at Azienda Ospedaliero Universitaria Policlinico di Modena from 2000 to 2020
- •Histologic diagnosis of endometriosis before pregnancy for case group
- •Age matched healthy patients for control group
排除标准
- •Clinical records not available
结局指标
主要结局
Gestational diabetes
时间窗: after 18 weeks' pregnancy
fasting blood glucose \>17 mmol/L
Postpartum hemorrhage
时间窗: Time of delivery
Greater than 500 mL estimated blood loss in a vaginal delivery or greater than 1000 mL estimated blood loss at the time of cesarean delivery
Birth-weight
时间窗: Time of delivery
small for gestational age (birth weight below the 10th percentile) or large for gestational age (birth weight over the 90th percentile)
Preterm delivery
时间窗: Time of delivery
Incidence of delivery before 37 weeks of pregnancy
Gestational hypertension
时间窗: after 20 weeks' gestation
blood pressure persistently \> 140/90 mm Hg
Assisted reproduction technologies
时间窗: before pregnancy
Patients who referred to assisted reproduction technologies
Cesarean Section
时间窗: Time of delivery
Robson Classifications
Apgar scores
时间窗: Time of delivery
Apgar scores
次要结局
未报告次要终点
研究者
Carlo Alboni, MD, PhD
Dr. Carlo Alboni MD, PhD Head of Minimally Invasive and Robotic Gynecologic Surgery Unit University Hospital of Modena - Italy
Azienda Ospedaliero-Universitaria di Modena