Impact of Endometriosis on Pregnancy and Delivery - a Retrospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,762
- 试验地点
- 1
- 主要终点
- pregnancy rate
研究概览
简要总结
Purpose:
To study the impact of endometriosis on subsequent pregnancy and delivery.
Methods:
retrospective analysis by questionnaire / interview of cases (endometriosis laparoscopically removed / child wish) vs. controls (endometriosis laparoscopically excluded / child wish) from the University Hospital Muenster, Germany, treated between 2009 and 2016; analysis of pregnancy rate, mode of delivery and complications using Clavien-Dindo-classification, role of deep infiltrating endometriosis using ENZIAN classification; data analysis using t-test with p < 0.050% being considered significant.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •cases: Operation because of endometriosis at the endometriosis Center, University Hospital Muenster, child wish, wants to participate, correct age group
- •controls: Operation because of sterility, exclusion of endometriosis during this Operation, child wish, wants to participate, correct age group
排除标准
- •cases / controls: declines participation, incorrect age Group, no child wish
结局指标
主要结局
pregnancy rate
时间窗: through study completion, an average of 1 year
pregnancy rate
complications
时间窗: through study completion, an average of 1 year
complications during pregnancy, delivery, puerperium
次要结局
未报告次要终点
研究者
Dr. med. Sebastian Daniel Schäfer
Head of Gynecology
University Hospital Muenster