COMPARISION OF THREE VERSUS MORE THAN THREE DOSES OF STREPTOKINASE, INSTILLED IN PLEURAL CAVITY IN CHILDREN WITH PUS IN PLEURAL CAVITY: AN OPEN LABEL RANDOMISED CONTROLLED TRIA
Not Applicable
Completed
- Conditions
- Health Condition 1: J869- Pyothorax without fistula
- Registration Number
- CTRI/2022/11/047575
- Lead Sponsor
- Post Graduate Institute of Medical Education & Research, Chandigarh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 53
Inclusion Criteria
Children less than 18 years of age with empyema. There is no lower cut off for age.
Empyema will be defined as presence of pus on a diagnostic pleural tap in children with clinical and/or radiological features consistent with pneumonia and parapneumonic pleural effusion ?.
Exclusion Criteria
1.Prior chest tube drainage with use of intrapleural fibrinolytics or any surgical intervention
2.Contra-indications to fibrinolytic therapy viz
3Known Coagulopathy or Bleeding disorders
4Confirmed Pneumothorax or bronchopleural fistula
5Head trauma during the preceding 2 weeks
6Children with prior microbiologically confirmed tuberculosis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method