Comparison between two schedules of giving Hepatitis B immunisation in unimmunised HIV-positive children.
Not Applicable
- Conditions
- Health Condition 1: null- HIV-infected children aged 18 months to 12 years
- Registration Number
- CTRI/2017/12/010816
- Lead Sponsor
- niversity College of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
HIV positive children receiving ART, who have not received any immunisation against Hepatitis B
Exclusion Criteria
Children who are Hepatits B surface antigen positive, suffering from Hepatitis C and immunological failure
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Anti HBs titres in both groups after completion of primary immunization scheduleTimepoint: 7 months after first dose of recombinant Hepatitis B vaccine
- Secondary Outcome Measures
Name Time Method 1Proportion of good responders in both groups <br/ ><br>2Proportion of non-responders in both groups <br/ ><br>3Anti HBs titres at 12 months in both groups <br/ ><br>Timepoint: 12 months after receiving the first dose of recombinant hepatitis B vaccine in both groups; 3 months after thr first dose of hepatitis B vaccine in 4 dose vaccine group