Effect of protein intake on skeletal muscle health among healthy Indian adults
- Registration Number
- CTRI/2018/12/016777
- Lead Sponsor
- utricia International Pvt Ltd
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Healthy controls
BMI: 18.5- 24.9 kg/m2
Muscle strength < 1 SD from Indian data set
1. H/O chronic diseases (Prediabetes, Type 2 DM, Hypertension, tuberculosis, cancer, chronic renal failure, ischemic heart disease, infections[tuberculosis, typhoid, dengue, etc. in the last 3 months etc)
2. H/O allergy to any form of protein intake (ex: soy)
3. Lactose intolerance
4. Alcohol intake greater than 2 STD per day
5. Any form of anaemia
6. Any form of peripheral neuropathy
7. Muscular dystrophies
8. Any form of joint injuries (knee and wrist)
9. Any form of surgeries on knee and wrist
10. History of osteoarthritis
11. Pregnancy
12. Consumption of protein supplements/nutritional supplement or Excess intake of protein than recommended
13. Those who exercise regularly (any form of resistance exercise/ heavy exercise, etc.)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To study the acute effect of (12g) protein consumption on the changes in amino acid pool (through amino-acidomics) and skeletal muscle health (strength, endurance and fatigability) among healthy Indian adults. <br/ ><br>2. To study the combined effect of 8 week protein supplementation and aerobic exercise (150 min brisk walking) on the changes in skeletal muscle health and amino acid pool among healthy Indian adults.Timepoint: 1.Acute study- Baseline, Day 7 <br/ ><br> <br/ ><br>2. Chronic study- Baseline, end of 8th week
- Secondary Outcome Measures
Name Time Method To study the combined effect of 8 week protein supplementation and aerobic exercise (150 min brisk walking) on the changes in skeletal muscle health and amino acid pool among healthy Indian adults.Timepoint: Chronic study- Baseline, end of 8th week