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Dexmedetomidine versus fentanyl as adjuvants to TIVA in craniotomies

Phase 4
Conditions
Health Condition 1: O- Medical and Surgical
Registration Number
CTRI/2024/03/064677
Lead Sponsor
ALL INDIA INSTITUTE OF MEDICAL SCIENCES
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Patients between 18-70 years of age including all genders.

2. American Society of Anaesthesiologists Physical status I to III.

3. Scheduled for elective craniotomy for supratentorial brain tumors under general anaesthesia.

Exclusion Criteria

1.Patients refusing to give consent.

2.Patient with body mass index = 35 kg/m².

3.Pregnant patients.

4.Patients allergic to any of the study drugs.

5.Preoperative GCS less than 13.

6.Patients with bleeding diathesis

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To assess the mean propofol consumption at the end of the surgery (in mcg/kg/min) in all the patients.Timepoint: At the end of the surgery
Secondary Outcome Measures
NameTimeMethod
To compare the intra-operative hemodynamic profile between the two groups.Timepoint: At 5-minute intervals till 15 minutes after induction, followed by every 30 minutes till the end of the surgery
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