To evaluate the effect of dexmedetomidine premedication on sedation in children undergoingMRI Brai
Phase 3
- Conditions
- Health Condition 1: F71- Moderate intellectual disabilities
- Registration Number
- CTRI/2020/10/028399
- Lead Sponsor
- Institutional Review Board IRB Christian Medical College Vellore
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All ASA I, II children under the age of 1-15 years
who are posted for MRI Brain
Exclusion Criteria
1. Difficult IV access requiring sevoflurane for more than 5 minutes
2. Pre induction haemodynamic instability (bradycardia, tachycardia,
hypotension)or respiratory vital / danger signs
( Active respiratory infection, airway obstruction, tachypnea, mild
wheeze)
3. Children taking more than two antiepileptic drugs
4. Known allergy to study drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare Recovery time of two techniques by using Ramsay sedation scale scoreTimepoint: To compare Recovery time of two techniques - Time from discontinuation of study drugs till Ramsay sedation scale <br/ ><br>score 2
- Secondary Outcome Measures
Name Time Method To compare time to induction, number of interruption of scan sequences, total dose <br/ ><br>of propofol administered and adverse event profile among two groups.Timepoint: Interruption of scan sequences - Visualized gross movements as noted from MRI <br/ ><br>console or motor artefact interrupting scan sequences <br/ ><br>Time to induction â?? Time from starting IV induction with study drugs till Ramasay sedation Scale score of 5 or 6 <br/ ><br>Total dose of propofol administered <br/ ><br>Adverse event profile -Apnea, airway obstruction,Moderate and mild hemoglobin oxygen <br/ ><br>desaturation, bradycardia and tachycardia <br/ ><br>Vitals will be monitored at baseline and then every 5 minutes till discharge