Study of effectiveness of dexmedetomidine, when added to local anaesthetic, in paravertebral block before breast cancer surgery
Phase 3
Completed
- Conditions
- Health Condition 1: null- Breast Cancer
- Registration Number
- CTRI/2012/11/003084
- Lead Sponsor
- niversity College of Medical Sciences and Guru Teg Bahadur Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 45
Inclusion Criteria
ASA I/II/III females,undergoing Modified Radical Mastectomy or Breast Conservation Surgery with Axillary Lymph Node Dissection.
Exclusion Criteria
• Patients undergoing bilateral breast surgery or breast reconstruction
• Contra-indications for PVB e.g. patientâ??s refusal, infection at the injection site, patients on anticoagulant therapy or having abnormal coagulation profile or hypersensitivity to local anaesthetic agents
• Patients on chronic antiemetics or chronic pain medication
• Pregnant patients
• Obese patients with BMI more than 30 kg/m2
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method â?¢ Cumulative IV morphine consumption over 24 hours <br/ ><br>â?¢ Pain scores at rest and active movement of ipsilateral arm <br/ ><br>Timepoint: During 24 hours after surgery
- Secondary Outcome Measures
Name Time Method â?¢ Nausea/Vomiting <br/ ><br>â?¢ Pruritus <br/ ><br>â?¢ Bradycardia/hypotension <br/ ><br>â?¢ Patient satisfaction with pain relief <br/ ><br>Timepoint: During 24 hours after surgery