Fast Track Laparoscopic Surgery: A Better Option for Treating Colorectal Cancer Than Conventional Laparoscopic Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 70
- 主要终点
- Length of hospital stay
研究概览
简要总结
To compare the outcomes of fast track laparoscopic surgery and conventional laparoscopic surgery.
详细描述
Method: This study is a blinded randomized trial. 70 patients with colorectal cancer will undergo laparoscopic colorectal resection, and will be divided into two groups. Protocols for fast-track group includes skipping preoperative mechanical bowel preparation, early restoration of diet and early postoperative ambulation. Outcome measures, length of hospital stay, postoperative surgical stress response (C reactive protein) and postoperative complications will be compared between the two groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- — 至 75 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≤75 years
- •Good nutrition
- •no systemic infection
- •Elective laparoscopic surgery
排除标准
- •Age >75 years
- •Malnutrition or an organ system infection
- •Associated with obstruction, bleeding, emergency surgery or surgical intervention
- •Tumor with extensive metastasis
- •Before operation patient was fasting, underwent gastrointestinal decompression and received nutritional support
- •Previous history of abdominal surgery
- •Patient had previously undergone gastrostomy
结局指标
主要结局
Length of hospital stay
时间窗: with the first 30 days(plus or minus 3days) after surgery
Postoperative days
时间窗: with the first 30 days(plus or minus 3days) after surgery
First flatus time
时间窗: with the first 30 days(plus or minus 3days) after surgery
First defecation time
时间窗: with the first 30 days(plus or minus 3days) after surgery
solid diet time
时间窗: with the first 30 days(plus or minus 3days) after surgery
次要结局
- Analgesics(with the first 30 days(plus or minus 3days) after surgery)
- CRP (mg/L)(with the first 30 days(plus or minus 3days) after surgery)
- Complications:anastomotic leakage,intestinal obstruction,wound infection(one year)
研究者
Quan Wang
Deputy Director of General Surgery
The First Hospital of Jilin University