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Clinical Trials/CTRI/2011/09/002013
CTRI/2011/09/002013
Completed
未知

laparoscopic versus open surgery- a comparative evaluation of hemodynamic, blood gases and acid-base changes in children undergoing abdominal operations

lady hardinge medical college1 site in 1 country60 target enrollmentFebruary 11, 2009

Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
lady hardinge medical college
Enrollment
60
Locations
1
Primary Endpoint
heart rate- no significant change,
Status
Completed
Last Updated
14 years ago

Overview

Brief Summary

The aim of the study was to evaluate and compare hemodynamic changes, blood gas and acid-base parameters, duration of hospital stay and any complications which occurred. An attempt was also made to correlate PaCO2 to EtCO2 changes.

in our study, we have not found any significant change in heart rate.

both, systolic and diastolic BP values were higher in laparoscopic group after creation of pneumoperitoneum,

PH values were decreased after creation of pneumoperitoneum

Registry
ctri.nic.in
Start Date
February 11, 2009
End Date
TBD
Last Updated
14 years ago
Study Type
Observational
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • ASA I & II, for abdominal surgery.

Exclusion Criteria

  • children with any congenital anomaly, difficult intubation, ASA III & IV.

Outcomes

Primary Outcomes

heart rate- no significant change,

Time Frame: hemodynamic parameters- baseline and then every 5 minutes till creation of pneumoperitoneum after that every 15 minutes till 1 hour and then every 30 minutes till the end of procedure. | acid- base and blood gases- i)after induction | ii)15 minutes after creation of pneumoperitoneum | iii)post extubation

BP- increased after creation of pneumoperitoneum,

Time Frame: hemodynamic parameters- baseline and then every 5 minutes till creation of pneumoperitoneum after that every 15 minutes till 1 hour and then every 30 minutes till the end of procedure. | acid- base and blood gases- i)after induction | ii)15 minutes after creation of pneumoperitoneum | iii)post extubation

pCO2 values increased after creation of pneumoperitoneum and then came back to baseline level 10-15 minutes after desufflation

Time Frame: hemodynamic parameters- baseline and then every 5 minutes till creation of pneumoperitoneum after that every 15 minutes till 1 hour and then every 30 minutes till the end of procedure. | acid- base and blood gases- i)after induction | ii)15 minutes after creation of pneumoperitoneum | iii)post extubation

EtCO2 values were significantly higher in laparoscopic group.

Time Frame: hemodynamic parameters- baseline and then every 5 minutes till creation of pneumoperitoneum after that every 15 minutes till 1 hour and then every 30 minutes till the end of procedure. | acid- base and blood gases- i)after induction | ii)15 minutes after creation of pneumoperitoneum | iii)post extubation

Secondary Outcomes

  • i)duration of surgery was similar in both the groups(ii)duration of hospital stay was longer in open surgery group)

Study Sites (1)

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