Prospective Randomised Study Comparing Laparoscopic Versus Open Surgery in Patients With Rectal Cancer
Phase 3
Completed
- Conditions
- RECTAL CANCER
- Registration Number
- NCT00782457
- Lead Sponsor
- Hospital Universitario Virgen de la Arrixaca
- Brief Summary
The aim of this study is to compare laparoscopic versus open approach on the surgical treatment of mid and low-lying rectal cancer, both performed by the same surgical team with experience in open colorectal surgery and advanced laparoscopic surgery, assessing preoperative and anatomopathological results and long-term outcome.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
- Mid- and low-lying rectal cancer (between 0 and 11 cm from the anal margin)
- Histology of adenocarcinoma
Exclusion Criteria
- Locally advanced disease (T4)
- Emergency surgery
- Rectal cancer over familial colic polyposis
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Lymph nodes isolated, circumferential margin involved, rate of complications and length of stay 1 month
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms by which laparoscopic surgery affects tumor recurrence in rectal cancer patients compared to open surgery?
How does laparoscopic resection compare to open surgery in terms of oncological outcomes for mid and low-lying rectal cancer in phase 3 trials?
Are there specific biomarkers that predict better long-term survival outcomes with laparoscopic versus open rectal cancer resection?
What are the potential adverse events associated with laparoscopic versus open surgical approaches for rectal cancer and their management strategies?
How does laparoscopic rectal cancer surgery compare to robotic-assisted approaches in terms of lymph node yield and margin status assessment?