Priority to Cryopreservation Strategy (PCS) in IVF-ICSI Cycles

Not Applicable

Recruiting

• Conditions: Infertility; Cryopreservation; IVF; ICSI
• Interventions: Procedure: Priority to freeze; Procedure: Fresh embryo transfer

• Registration Number: NCT03913208
• Lead Sponsor: Tanta University

Brief Summary

This multicentre randomized controlled trial will be done to evaluate a new strategy in IVF-ICSI practice that gives that priority to freeze for the embryos and goes to fresh embryo transfer only if at least one set of same quality embryos is available for cryopreservation.

Detailed Description

This study will be a non-blind, prospective, double-armed, randomized clinical trial. The study will be conducted at five centers, the Educational Hospital Fertility Unit of Tanta University, the fertility center of Cairo University, the fertility center of Assiut University, the Egyptian Consultants Fertility Center in Tanta, and MRC fertility center in Cairo from May 1st 2019 till the end of the objected number. The study will be conducted in accordance with the Declaration of Helsinki, and all participants should sign a written informed consent before inclusion in the study.

Study Timeline

• Study First Submitted: 2019-04-10
• Study First Submitted QC: 2019-04-10
• Study First Posted: 2019-04-12
• Study Start: 2019-05-01
• Status Verified: 2023-07
• Last Update Submitted: 2023-07-15
• Last Update Posted: 2023-07-18
• Primary Completion: 2024-12-31
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 1000

Inclusion Criteria

• Candidates for IVF/ICSI
• Presence of good number of embryos > 5

Exclusion Criteria

• Low quality embryos
• Low ovarian reserve
• Low number of embryos

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Study group	Priority to freeze	Will be subjected to priority to freeze
Control group	Fresh embryo transfer	Will receive fresh embryo transfere

Primary Outcome Measures

Name	Time	Method
Cumulative pregnancy rates	3 months	The number of pregnant women in both groups after 3 cycles

Secondary Outcome Measures

Name	Time	Method
Failure of pregnancy	3 months	Failed ICSI

Trial Locations

Locations (1)

Ayman Shehata Dawood; 🇪🇬 Tanta, Egypt