Establishment and Clinical Validation of New Technologies for Accurate Screening of Colorectal Cancer Based on Multi-omics
- Conditions
- Colorectal Cancer
- Registration Number
- NCT04913233
- Lead Sponsor
- Second Affiliated Hospital, School of Medicine, Zhejiang University
- Brief Summary
Background:
The current screening techniques for colorectal cancer include colonoscopy, fecal occult blood, and high-risk factor questionnaires. However, the colorectal cancer screening technology that has been widely used at present cannot take into account sensitivity and specificity, and the tumor detection rate is low.
The purpose of research:
1. Build a new type of population colorectal cancer precision screening technology program;
2. Improve the detection rate of colorectal cancer in the population by new methods (compared with the existing domestic advanced technology) by ≥20%, and improve the specificity of colorectal cancer screening by ≥15% without significantly reducing the sensitivity.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 9000
Age: 40-74 years old
- Combine severe disorders to make it unsuitable for colonoscopy
- Combine other tumors
- Mental and behavioral abnormalities do not cooperate with the screener
- Researchers believe that other reasons are not suitable for enrollment
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Colorectal cancer detection rate in the population through study completion, an average of 3 years Colorectal cancer detection rate in the population
Colorectal cancer screening specificity through study completion, an average of 3 years Colorectal cancer screening specificity
Colorectal cancer screening sensitivity through study completion, an average of 3 years Colorectal cancer screening sensitivity
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (3)
Jiashan County Cancer Prevention and Treatment Institute
🇨🇳Jiashan, Zhejiang, China
Lanxi City People's Hospital, Linjiang Hospital
🇨🇳Lanxi, Zhejiang, China
Chinese Medicine Hospital of Haining City, Haining Cancer Preventional and Treatment Research Institute
🇨🇳Haining, Zhejiang, China