CTRI/2025/05/086230尚未招募4 期
A Comparative study of efficacy and safety of intralesional platelet rich fibrin vs intralesional platelet rich plasma in patients of alopecia areata
Dr RPGMC Tanda1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年5月13日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Investigator assessment scale
研究概览
简要总结
Alopecia Areata is a common autoimmune disease with non-scarring type of hair loss without any clinical inflammatory signs, most treatments require multiple sittings of treatment and multiple needle pricks, some of treatment can cause atrophy, recurrence rates are also high. In this study aim is to study the efficacy and safety of platelet rich fibrin in the treatment of alopecia areata and to compare efficacy and safety of intralesional platelet rich fibrin vs intralesional platelet rich plasma in patients of alopecia areata.
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of AA between Age group 18 to 50 years.
- •Diagnosed clinically with alopecia areata of scalp coming to skin opd.
- •Patients willing to give consent for inclusion in study
- •Patients who have not taken medical treatment for AA in any form for the last 6 months.
- •Control group includes age and sex matched individuals without history of AA
- •Platelet count more than 1.5 lac.
排除标准
- •Patients with alopecia other than alopecia areata.
- •Patients with active infection at the local site.
- •Patients having keloidal tendency.
- •Patients with blood coagulopathies.
- •Platelet count less than 1.5 lacs per µl.
- •Patients who are immunosuppressed (HIV, malignancy, steroid or chemotherapy).
- •Pregnancy or lactation
- •Patients not willing to give written informed consent.
- •Patient on anticoagulation.
结局指标
主要结局
Investigator assessment scale
时间窗: Baseline, 2, 4, 6 months
次要结局
- Trichoscopic Analysis(1 Size of alopecia patch using measuring tape)
- Patients self-assessment(Baseline, 2, 4, 6 months)
- Improvement assessment based on SALT score(Baseline, 2, 4, 6 months)
研究者
研究点 (1)
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