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Examination of Differential Valuation of Leisure Items and Attention as Reinforcers in Children With Autism

Not Applicable
Completed
Conditions
Autism
Interventions
Behavioral: Training trials
Behavioral: Progressive Ratio Session
Behavioral: Re-test
Behavioral: Pairing Protocol
Registration Number
NCT03152383
Lead Sponsor
Emory University
Brief Summary

The purpose of this study is to compare how children with autism, typically developing children, and children with other developmental delays value social attention and toys. The first part of the study seeks to determine whether breakpoints when responding on progressive ratio (PR) schedules can be used to determine the value of leisure items and attention. By comparing the breakpoints obtained for leisure items and attention, the researchers will determine the differential valuation of leisure items and attention. It is anticipated that the manner in which individuals with an autism spectrum disorder (ASD) diagnosis and those who do not will differ with respect to the degree to which they value these two types of stimuli. The second part of the study seeks to determine whether an intervention in which social attention is paired with primary reinforcers impacts responding during the PR assessment, in children with ASD.

Detailed Description

The three core features of autism spectrum disorder (ASD) are impairments in social interaction, restricted range of interest, and stereotyped/repetitive behavior. However, autism is a heterogeneous disorder, and individuals with a diagnosis vary widely in specific presentation. For example, despite an overall impairment in social behavior, some individuals with an autism diagnosis still frequently initiate social interactions with others. In contrast, others may engage in problem behaviors maintained by escape or avoidance of social interactions.

A progressive ratio (PR) assessment is one method for directly quantifying the degree to which an individual values a particular stimulus or event. Within a PR assessment, reinforcement occurs under schedule requirements that increase following each set of responses within a single session until responding ceases. The highest schedule requirement completed (i.e., breakpoint) can then be used as a measure of how much an individual is willing to respond for a given stimulus.

The study will include about 65 children, 25 children with ASD and 15 typically developing children, and 25 children with developmental disabilities other than ASD. Children with autism, typically developing children, and children with non-ASD developmental delays other than ASD will be compared in terms of how they value social attention and toys. The child participants will be asked to do an action, such as pressing a button, to receive either an item or attention. At first, the participants will only be required to do the action once, but after the first time the children will be required do more and more before they can get the item or attention. Eventually, most children stop responding for the preferred item or attention. The study will consider the child as done working when they go for one minute without performing the action. Sessions will end after 30 minutes if the child keeps working without stopping. This study will examine how many times the child will respond for items and attention. 15 of the children with ASD will be asked to come back for an additional appointment one week after they complete the assessment of how they value attention and toys. The PR assessment will be repeated see if the children respond the same way at different times.

The second part of the study will include 10 children diagnosed with ASD ranging in age from two to six. All of the procedures described in part one of the study will be included. The PR assessment will be completed prior to intervention and again after intervention. All appointments will be conducted over a maximum of 4 weeks. The intervention will be based on the principals of respondent conditioning; social interaction will be paired with the delivery of other reinforcers, such as edible items, to increase the value of social interaction. Sessions will be conducted 5 days per week and will be up to two hours long. Following the intervention, the participant will repeat the PR assessment in order to assess whether the intervention increased the value of social interaction.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
64
Inclusion Criteria

Not provided

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Exclusion Criteria

Not provided

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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Typically developingTraining trialsChildren who are typically developing
Autism Spectrum DisorderTraining trialsChildren diagnosed as having autism spectrum disorder
Autism Spectrum DisorderProgressive Ratio SessionChildren diagnosed as having autism spectrum disorder
Other Developmental DelayProgressive Ratio SessionChildren diagnosed with a developmental delay other than autism spectrum disorder
Autism Spectrum DisorderRe-testChildren diagnosed as having autism spectrum disorder
Autism Spectrum DisorderPairing ProtocolChildren diagnosed as having autism spectrum disorder
Typically developingProgressive Ratio SessionChildren who are typically developing
Other Developmental DelayTraining trialsChildren diagnosed with a developmental delay other than autism spectrum disorder
Primary Outcome Measures
NameTimeMethod
Change in breakpointsAssessment 1 through repeat assessment (up to 4 weeks)

For children receiving the intervention the change between breakpoints across the two PR assessments conducted before and after intervention will be examined.

Breakpoint achieved for each stimulusUp to one week

The highest schedule requirement completed (i.e., breakpoint) is used as a measure of how much an individual is willing to respond for a given stimulus.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Marcus Autism Center

🇺🇸

Atlanta, Georgia, United States

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