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Evaluating the efficacy of Metformin with Isotretinoin in the treatment of acne

Phase 3
Recruiting
Conditions
Acne.
Acne
Registration Number
IRCT20140624018210N8
Lead Sponsor
Iran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
70
Inclusion Criteria

Start acne from adolescence and continue acne until the age of 25
Start acne from adolescence and continue after 25 years
Start acne after 25 years

Exclusion Criteria

History of taking Metformin or Isotretinoin
History of chronic diseases of kidney, liver or heart

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Changes of acne severity. Timepoint: 1, 3 and 6 months after intervention. Method of measurement: Clinical examination.
Secondary Outcome Measures
NameTimeMethod
Fasting blood sugar. Timepoint: Before starting the intervention and 6 months after the intervention. Method of measurement: Blood test.;Cholesterol. Timepoint: Before starting the intervention and 6 months after the intervention. Method of measurement: Blood test.;Triglyceride. Timepoint: Before starting the intervention and 6 months after the intervention. Method of measurement: Blood test.
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