Measurement of the antimicrobial cefuroxime in subcutaneous and bone tissue using microdialysis

• Conditions: Orthopedic infections; MedDRA version: 16.0Level: LLTClassification code 10050155Term: Knee prosthesis insertionSystem Organ Class: 100000004865; Therapeutic area: Diseases [C] - Bacterial Infections and Mycoses [C01]

• Registration Number: EUCTR2013-001138-17-DK
• Lead Sponsor: Orthopedic Research in Aarhus

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-07-11
• Last Update Posted: 5 August 2014

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: Male
• Target Recruitment: Not specified

Inclusion Criteria

- The patients must be scheduled for a knee prosthesis. The indication must be arthrosis
- Normal kidney function.
- Male gender
- The patients must be competent
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 6
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 12

Exclusion Criteria

- Allergy to cefuroxime og vancomycin
- Ongoing treatment with cefuroxime
- Female gender

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified