Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis

• Conditions: Asthma; Rhinitis
• Interventions: Other: regular treatment

• Registration Number: NCT00952835
• Lead Sponsor: Universita di Verona

Brief Summary

In this study will be consecutive enrolled children with asthma (classified according to GINA guidelines) and rhinitis (classified by ARIA guidelines); the investigators will research clinical personal and parental history regarding allergic diseases, exposition to passive smoking and interpretate hematochemical parameters markers of atopy. Skin Prick Tests will be performed. In this study the investigators will evaluate lung function parameters (spirometry with bronchial reversibility test and exercise induced bronchoconstriction, oscillometry, respiratory plethysmography, etc.), airway inflammatory indices such as exhaled nitric oxide at different flows, exhaled and nasal temperature, nasal cytology.

The aim of the study will be to evaluate possible correlation between these different parameters and clinical status of the patients.

Detailed Description

Each patients will be evaluated by spirometry and then he will undergo exercise challenge in order to evaluate exercise-induced bronchoconstriction as a marker of asthma control. The test of the challenge will be correlate with childhood Asthma control test score,levels of control (GINA classification)and the different markers of airway inflammation and atopy.

Study Timeline

• Study Start: 2009-07
• Study First Submitted: 2009-08-03
• Study First Submitted QC: 2009-08-03
• Study First Posted: 2009-08-06
• Status Verified: 2013-06
• Last Update Submitted: 2013-06-18
• Last Update Posted: 2013-06-19
• Primary Completion: 2013-12
• Study Completion: 2014-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• patient with asthma and rhinitis

Exclusion Criteria

• age <5 years
• chronic respiratory diseases

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
asthma and rhinitis control	regular treatment	-

Primary Outcome Measures

Name	Time	Method
Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis	Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis

Trial Locations

Locations (1)

Pediatric department University of Verona; 🇮🇹 Verona, Italy