RaDIANT Health Systems Intervention

Not Applicable

Not yet recruiting

• Conditions: End Stage Renal Disease (ESRD); Kidney Disease

• Registration Number: NCT07033117
• Lead Sponsor: Indiana University

Brief Summary

The overarching goal of the proposed study is to determine whether the addition of structural interventions at the health system level targeting upstream barriers in the transplant process will improve access to transplant evaluation start.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-06
• Study First Submitted: 2025-06-13
• Study First Submitted QC: 2025-06-13
• Last Update Submitted: 2025-06-13
• Study First Posted: 2025-06-24
• Last Update Posted: 2025-06-24
• Study Start: 2025-08-01
• Primary Completion: 2026-07-31
• Study Completion: 2026-07-31

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 14000

Inclusion Criteria

• Five large transplant centers (Emory Transplant Center and Piedmont Transplant Center in Atlanta, GA; Medical University of SC; Duke University in Durham, NC; and Indiana University in Indianapolis, IN) ~800 referring dialysis center referring to these transplant centers

Exclusion Criteria

• Individuals referred, initiating evaluation, and waitlisted at non-participating start centers

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Change in transplant evaluation start within 6 months of transplant referral	Baseline, Post Intervention (Up to one year)	The difference in the proportion of patients starting transplant evaluation within 6 months of being referred from baseline to up to one-year post-intervention

Secondary Outcome Measures

Name	Time	Method
Change in transplant waitlisting	Baseline, Post Intervention (Up to one year)	The difference in the proportion of patients waitlisted from baseline and up to one-year post-intervention
Change in transplant receipt among those who were waitlisted	Baseline, Post Intervention (Up to one year)	The difference in the proportion of patients who received a transplant among those who were waitlisted from baseline and up to one-year post-intervention

Trial Locations

Locations (5)

Piedmont Transplant Institute; 🇺🇸 Atlanta, Georgia, United States

Emory Transplant Center; 🇺🇸 Atlanta, Georgia, United States

IU Health Transplant - Indianapolis; 🇺🇸 Indianapolis, Indiana, United States

Duke Transplant Center; 🇺🇸 Durham, North Carolina, United States

MUSC Mid-Carolinas Transplant Center; 🇺🇸 Lancaster, South Carolina, United States