Prevalence of Malnutrition in Surgery
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 700
- 试验地点
- 8
- 主要终点
- Malnutrition
研究概览
简要总结
Nutritional disorders are highly prevalent in gastrointestinal cancer patients undergoing surgery and have shown to contribute significantly in short, mid and long-term clinical outcome. Although increasing evidence and expert suggestions there is still inadequate awareness about the clinical relevance of nutritional and metabolic alterations in surgical oncologic patients.
详细描述
Nutritional disorders are highly prevalent in cancer patients and have shown to contribute significantly in short-, mid- and long-term clinical outcome. The prevalence of malnutrition is reported between 25% and over 70% based on nutritional assessments. Nutritional disorders represent an important risk factor for the occurence of postoperative complications.
Main obstacles to improving nutritional care include lack of awareness for the problem among the general public and lack of awareness among decision makers and even care providers.
Considering the high prevalence of malnutrition and its repercussions in patient morbidity-mortality and healthcare cost, nutritional screening measures must be included in an integrated nutritional care plan for patients before surgery and while in the hospital.
The PRoMiS study was conceived to quantify nutritional disorders among gastrointestinal cancer patients undergoing surgery in Italy. The data obtained will contribute to increase the awareness of nutritional disorders among oncology surgical patients and their impact on clinical outcome, favoring the inclusion of the initial assessment of nutritional status before surgery and of the nutritional intervention.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who are candidates for surgery for gastrointestinal cancer (esophagus, stomach, small intestine, pancreas, biliary tract, colon, rectum, liver)
- •Diagnosis of malignant solid tumor
- •Age> 18 years
- •Informed consent
排除标准
- •Uncontrolled metabolic disorders
- •Uncompensated heart failure
- •Severe psychiatric disorders
- •Appropriate logistical support for participation in the study.
结局指标
主要结局
Malnutrition
时间窗: Pre-operative
Malnutrition will be assessed by Malnutrition Universal Screening Tool (MUST)
次要结局
- Post-operative complications(Hospital discharge (10-15 days))