Does stage of menstrual cycle affect recovery after surgery in premenopausal women?

Not Applicable

Completed

• Conditions: Postoperative recovery; Anaesthesiology - Pain management; Reproductive Health and Childbirth - Menstruation and menopause; Menstrual cycle; Postoperative nausea and vomiting; Postoperative pain management; Anaesthesiology - Anaesthetics

• Registration Number: ACTRN12618000240246
• Lead Sponsor: Epworth Richmond

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-02-14
• Study Completion: 2021-11-01
• Last Update Posted: 30 May 2022

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 191

Inclusion Criteria

1. premenopausal women aged 18 to 45 years
2. having a general anaesthetic for elective wisdom teeth extraction or laparoscopic cholecystectomy

Exclusion Criteria

Participants will be excluded if they are
1. using hormonal contraception (oral contraceptive pill, hormone-impregnated intrauterine device, subcutaneous implants) or treated with sex hormone therapy for other reasons
2. pregnant or lactating
3. undergone a bilateral oophorectomy
4. known or suspected to be peri- or post-menopausal
5. unable to complete QoR-15 score
6. active cancer
7. systemic disease affecting daily function (ASA 3 or more)
8. contraindication to dexamethasone, current systemic steroid treatment for any reason, insulin-dependent diabetes mellitus
9. regular opioid use
10. previous recruitment in this study.

Study & Design

• Study Type: Observational
• Study Design: Not specified